Amitriptyline 37.5 mg by mouth twice daily. Available tablets are 75 mg. How many tablets should be given per dose?

0.25 tablets

0.5 tablets

When figuring out how many tablets to give, divide the amount you need per dose by the strength of one tablet. You need 37.5 mg per dose, and one tablet provides 75 mg. 37.5 ÷ 75 = 0.5, so half a tablet per dose. Since the plan is twice daily, you would give a half-tablet at each dose, totaling 75 mg per day. Just confirm that splitting a tablet is allowed for this medication and tablet design; if not, use a different strength or formulation.

0.75 tablets

1 tablet

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