Methyldopa 25 mg order. The available formulation is 50 mg per 5 mL. How many milliliters should be administered?

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Multiple Choice

Methyldopa 25 mg order. The available formulation is 50 mg per 5 mL. How many milliliters should be administered?

Calculating the correct dose from a liquid concentration involves using the amount of drug per milliliter. Here, 50 mg are in 5 mL, so the concentration is 50 mg ÷ 5 mL = 10 mg per 1 mL. To obtain a 25 mg dose, divide the desired amount by the concentration per milliliter: 25 mg ÷ 10 mg/mL = 2.5 mL. Check by reversing the calculation: 2.5 mL × 10 mg/mL = 25 mg. The other volumes would deliver different amounts (for example, 1.25 mL is 12.5 mg, 0.5 mL is 5 mg, and 5 mL is 50 mg), so 2.5 mL is the correct volume.

Calculating the correct dose from a liquid concentration involves using the amount of drug per milliliter. Here, 50 mg are in 5 mL, so the concentration is 50 mg ÷ 5 mL = 10 mg per 1 mL. To obtain a 25 mg dose, divide the desired amount by the concentration per milliliter: 25 mg ÷ 10 mg/mL = 2.5 mL. Check by reversing the calculation: 2.5 mL × 10 mg/mL = 25 mg. The other volumes would deliver different amounts (for example, 1.25 mL is 12.5 mg, 0.5 mL is 5 mg, and 5 mL is 50 mg), so 2.5 mL is the correct volume.

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